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ePatch

ePatch

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Category: Patch Clamp Amplifiers Tags: amplifiers, bridge recording, electrophysiology rig, extracellular recording, in vitro recording, in vivo recording, intracellular recording, oocyte recording, patch clamp, patch clamp rig, single electrode voltage clamp, two elecrode voltage clamp, xenopus recording
  • Overview
  • Details
  • Specifications
  • Downloads
  • References
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Overview

The world’s smallest integrated patch clamp amplifier and data acquisition system for whole-cell and single-channel recordings

A very low noise one channel amplifier enabling high bandwidth acquisitions for voltage-clamp measurements.

The miniaturized ePatch amplifier integrates in a small headstage the low-noise amplifier, the pulse generator and the digitizer into only 42 x 18 x 78 mm and it is connected directly to the USB port of a laptop without the need of any other external bulky digitizer and control unit.

Last Updated on October 10, 2024

Details

EZ Patch – the new ePatch software interface

EZ Patch software is the new patch-clamp electrophysiology software developed and released by Elements for easy control of the ePatch amplifier. EZ Patch allows:

  • Customizable user-friendly Windows-format interface
  • Real-time display of voltage and current digitized data
  • Parametric voltage protocols editor
  • Automatic or manual control of compensation settings
  • Membrane parameters estimation to keep track of cell health
  • Real-time data analysis (C-fast – estimation, noise, I/V graph, current histogram, etc.)
  • Digital LabBook
  • Data output saving formats: .abf
  • Available for Windows, coming soon for Mac OS

Last Updated on October 10, 2024

Specifications

  • Open input (RMS) noise: 115 fA rms @ 1kHz – 460 fA rms @ 10 kHz – 3.6 pA rms @ 100 kHz
  • Current ranges: ±200pA (Gain 2.25GΩ), ±2nA (Gain 225MΩ), ±20nA (Gain 22.5MΩ), ±200nA (Gain 2.25MΩ)
  • Parametric voltage protocols for pulse generator in the range of ± 500 mV
  • Available bandwidth between 62,5 Hz to 100 KHz
  • Max sampling rate: 200 ksps
  • C-fast – C-slow – R-series
  • C fast compensation range: 0-11 pF
  • R series compensation range: 0 -100 MΩ
  • Auto electrodes voltage offset fine compensation
  • Data output format .abf
  • Zap pulse
  • USB powered
  • Dovetail or rod bar mounting
  • Size & Weight: 42 x 18 x 78 mm, 200 g

Last Updated on October 10, 2024

Downloads

ePatch Literature:

ePatch Literature

Last Updated on October 10, 2024

References

  • Rational design of a mutation to investigate the role of the brain protein TRIP8b in limiting the cAMP response of HCN channels in neurons, A. Porro et al
  • The HCN domain couples voltage gating and cAMP response in hyperpolarization-activated cyclic nucleotide-gated channels, A. Porro et al
  • Actin filaments modulate electrical activity of brain microtubule protein two-dimensional sheets, M. R. Cantero et al
  • Investigating the effects of lamotrigine on HCN channels: a test case for a new miniaturized patch-clamp amplifier, A. Porro et al
  • Helices D and E of HCN4 channel tune the CAMP responsiveness, A. Porro et al

Last Updated on October 10, 2024

Ordering

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ePatch Low noise 1 channel integrated patch clamp amplifier and data aquisition system for whole-cell and single-channel recordings with EZPatch software

Last Updated on October 10, 2024

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Axon™ Digidata® 1550B Low-Noise Data Acquisition System plus HumSilencer Single Axis Manipulator and Controller
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