Overview
The Quartz MicroManifold® (QMM) technology from ALA incorporates quartz micro-capillaries coated with polyimide to make them flexible and damage resistant. Quartz capillaries are used to converge several perfusion inputs into a single output with a dead volume of ~ 90nL. Whether using to focally apply solution or to puff droplets of solution, a QMM allows for reproducible applications while still being low-maintenance.
Key features of QMM’s include:
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- Compatibility with ALA’s focal pressurized perfusion systems
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- Autoclavable materials which are inert, robust, and flexible
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- Manipulator holders for easy mounting onto a manipulator
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- Standard 4, 8, 12, 16, 24, or 32 inlet ports with silicone sleeves for easy connections
Options include:
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- 100μm or 200μm inner diameter inlet tubes and output tip (other sizes available)
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- Additional flush valve input
- Customizable number of inlet ports
The inlets allow for quick connection to tubing via the attached silicone sleeves or via optional compression fittings.
Last Updated on April 25, 2022
Details
The convergence zone is within a silicone sleeve that holds the tip in place and is easily removed. The precise microdimensions yield super fast application times when it is used as an applicator for various agents that need to be applied in rapid succession. Silicone adaptors at the inlets allow for connections to tubing.
Each Quartz MicroManifold® (QMM) is completely inert, durable, easy to clean, and can be mounted in any micromanipulator. QMM’scan be used wherever tiny amounts of liquid (mL to nL volumes) need to flow together to a single output or be directed at a microtarget like an individual cell.
Last Updated on April 25, 2022
Specifications
| Material |
Polyimide coated quartz |
| Standard inlet tube ID |
100µm or 200µm (other sizes available) |
| Standard inlet tube OD |
230µm (other sizes available) |
| Typical flush input tube ID |
200µm (other sizes are available) |
| Typical flush input tube OD |
360µm (other sizes are available) |
| Overall length |
3.25″/82.5mm |
| Typical dead volume |
~90nL |
Last Updated on April 25, 2022
References
Smith K.A., Prantzalos E.R., Anantharam A. (2020) Integrating Optical and Electrochemical Approaches to Assess the Actions of Dynamin at the Fusion Pore. In: Ramachandran R. (eds) Dynamin Superfamily GTPases. Methods in Molecular Biology, vol 2159. Humana, New York, NY. https://doi.org/10.1007/978-1-0716-0676-6_12
Bai, J-P, Xue, N, Lawal, O, Nyati, A, Santos-Sacchi, J, Navaratnam, D. Calcium-induced calcium release in proximity to hair cell BK channels revealed by PKA activation. Physiol Rep. 2020; 8:e14449. https://doi.org/10.14814/phy2.14449
Last Updated on April 25, 2022
Accessories
FEP-1
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: 4m clear Teflon tubing with 230um ID and 600um OD (for 100um ID QMM’s)
FEP-2: 4m clear Teflon tubing with 380um ID and 760um OD (for 200um ID QMM’s)
CF-1: Compression fitting for PE-10/FEP-1 tubing to 1/16″ ID tubing
CF-2: Compression fitting for PE-20/FEP-2 tubing to 1/16″ ID tubing
Last Updated on April 25, 2022
Ordering
| Part# |
Description |
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ALA QMM-__
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Quartz MicroManifold® perfusion outlet manifold with 100um or 200um ID (please specify) tubing and tip (other sizes available – please call or email to inquire) |
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ALA QMM-__WT
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Quartz MicroManifold®perfusion outlet manifold with 100um or 200um ID (please specify) tubing and tip (other sizes available – please call or email to inquire) and clear teflon tubing installed |
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ALA QMM-__/1
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Quartz MicroManifold® perfusion outlet manifold with 100um or 200um ID (please specify) tubing and tip (other sizes available – please call or email to inquire) and additional channel with 200um ID tube for flushing dead space |
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ALA QMM-__/1WT
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Quartz MicroManifold® perfusion outlet manifold with 100um or 200um ID (please specify) tubing and tip (other sizes available – please call or email to inquire), additional channel with 200um ID tube for flushing dead space, and clear teflon tubing installed |
|
ALA QMM-4UF
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Replacement 4-channel Quartz MicroManifold® for uFlow-4 |
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ALA QMM-8UF
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Replacement 8-channel Quartz MicroManifold® for uFlow-8 |
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ALA QMM CUSTOM
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Custom Quartz MicroManifold® perfusion outlet manifold – please call or email to inquire |
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ALA QTP-XXXY
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Replacement tip for Quartz MicroManifold®
XXX = tip ID in um (e.g. 100)
Y = tip length in mm (e.g. 5) |
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ALA Holder-QMM
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Quartz MicroManifold® holder with 4mm OD bar with 6mm OD removable adapter sleeve |
Standard Sizes: 4, 8, 12, 16, 24, 32
Last Updated on April 25, 2022
