Standard Harp Slice Grids

  • Model: HSG
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Description

HARP SLICE GRIDS™
Electrophysiology and imaging experiments with submerged slices won’t work if the slices are drifting during perfusion. Securing slices with homemade grids requires spending time gluing bits of wire and nylon together and testing them on valuable preparations. Using ALA’s HARP SLICE GRIDS™ will provide more consistent results and more time to do experiments.

Last Updated on March 6, 2025

Details

 

ALA’s HARP SLICE GRIDS™ are constructed with durable and inert glass-coated steel rings with polyimide-coated silica fibers that are available in suitable configurations for most preparations.
Polyimide coated silica fiber “strings” lie across the preparation. The thinness of the “strings” (~50-65μm OD) combined with relatively wide spacing (about 1mm) facilitates electrode or pipette access from above the preparation. These are ideal for classical electrophysiological recordings with slices in submerged or interface chambers.

Custom sizes available, minimums apply.

 

Last Updated on March 6, 2025

Specifications

String spacing is 1mm and each string is ~ 50-65μm thick

TYPE Dimensions
HSG-5A 9.5mm ID x 12mm OD x 0.5mm thick; 0.2g
HSG-5AD 9.5mm ID x 12mm OD x 1.0mm thick; 0.4g
HSG-5B 9.5mm ID x 12.75mm OD x 0.83mm thick; 0.4g
HSG-5BD 9.5mm ID x 12.75mm OD x 1.64mm thick; 0.8g
HSG-5C 6.4mm ID x 8mm OD x 0.5mm thick; 0.05g
HSG-5CD 6.4mm ID x 8mm OD x 1.0mm thick; 0.1g
HSG-5D 6.0mm x 3.3mm ID x 12.7mm OD x 0.54mm thick; 0.18g – oval interior
HSG-5DD 6.0mm x 3.3mm ID x 12.7mm OD x 1.07mm thick; 0.35g – oval interior
HSG-5E 4.8mm x 2.5mm ID x 9.5 mm OD x 0.5mm thick; .1g – oval interior
HSG-5ED 4.8mm x 2.5mm ID x 9.5 mm OD x .85mm thick; .2g – oval interior
HSG-5F 10.0mm ID x 13.8mm OD x 0.8mm thick; 0.18g – pick and place
HSG-5FD 10.0mm ID x 13.8 mm OD x 1.8mm thick; 0.33g – pick and place

Last Updated on March 6, 2025

Downloads

Manual Harp Slice Grid Literature

Last Updated on March 6, 2025

References

Sun, Y., Sommerville, N.R., Liu, J.Y.H., Ngan, M.P., Poon, D., Ponomarev, E.D., Lu, Z., Kung, J.S.C. and Rudd, J.A. (2020), Intra‐gastrointestinal amyloid‐β1–42 oligomers perturb enteric function and induce Alzheimer’s disease pathology. J Physiol. doi:10.1113/JP279919

https://physoc.onlinelibrary.wiley.com/doi/full/10.1113/JP279919

 

Ayton, S., Lei, P., Appukuttan, A.T. et al. Brain Zinc Deficiency Exacerbates Cognitive Decline in the R6/1 Model of Huntington’s Disease. Neurotherapeutics 17, 243–251 (2020). https://doi.org/10.1007/s13311-019-00785-6

 

Ciotu, C.I., Kistner, K., Kaindi, U., Millesi, F., Weiss, T., Radtke, C., Kremer, A., Schmidt et al Schwann cell stimulation induces functional and structural changes in peripheral nerves doi.org/10.1002/glia.24316

https://onlinelibrary.wiley.com/doi/full/10.1002/glia.24316

Last Updated on March 6, 2025

Ordering

String spacing is 1mm and the each string is ~ 50-65μm thick

Ordering Information
TYPE Description
HSG-5A 9.5mm ID x 12mm OD x 0.5mm thick; 0.2g – 5 pack
HSG-5AD 9.5mm ID x 12mm OD x 1.0mm thick; 0.4g – 5 pack
HSG-5B 9.5mm ID x 12.75mm OD x 0.83mm thick; 0.4g – 5 pack
HSG-5BD 9.5mm ID x 12.75mm OD x 1.64mm thick; 0.8g – 5 pack
HSG-5C 6.4mm ID x 8mm OD x 0.5mm thick; 0.05g – 5 pack
HSG-5CD 6.4mm ID x 8mm OD x 1.0mm thick; 0.1g – 5 pack
HSG-5D 6.0mm x 3.3mm ID x 12.7mm OD x 0.54mm thick; 0.18g – oval interior – 5 pack
HSG-5DD 6.0mm x 3.3mm ID x 12.7mm OD x 1.07mm thick; 0.35g – oval interior – 5 pack
HSG-5E 4.8mm x 2.5mm ID x 9.5 mm OD x 0.5mm thick; .1g – oval interior – 5 pack
HSG-5ED 4.8mm x 2.5mm ID x 9.5 mm OD x .85mm thick; .2g – oval interior
HSG-5F 10.0mm ID x 13.8mm OD x 0.8mm thick; 0.18g – pick and place – 5 pack
HSG-5FD 10.0mm ID x 13.8 mm OD x 1.8mm thick; 0.33g – pick and place – 5 pack

Last Updated on March 6, 2025

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